After applying 18.104.22.168.170418 to the GI HOME, creating the spfile in ASM was no longer possible. The ASM alert log showed
CRS-6706: Oracle Clusterware Release patch level ('2809840508') does not match Software patch level ('3372807730'). Oracle Clusterware cannot be started.
After stopping HAS, the cluster stack was not startable anymore.
I found the solution here: http://www.fahdmirza.com/2016/02/opatchauto-session-failed-parameter.html
Execute as root:
It will fix the issue and start HAS automatically.
Using configuration parameter file: grid_home/product/22.214.171.124/grid/crs/install/crsconfig_params CRS-4123: Oracle High Availability Services has been started.